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Operational Medicine 2001
Oxacillin (Bactocill)

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Category:

  • Antibiotic

Description:

  • Penicillinase-Resistant Penicillin

Indications:

  • Mild to moderate infections caused by penicillinase-producing staphylococci

  • Upper Respiratory Tract Infections

  • Localized soft tissue/skin infections

  • Lower Respiratory Tract Infections

  • Disseminated infections

Contraindications:

  • None

Precautions:

  • Pregnancy category B

  • Use with caution in patients with penicillin or cephalosporin allergy (5-10% chance of cross-reactivity)

  • Counsel patient to finish all medication to prevent development of resistance

  • Inform patient to take at even intervals, preferably around the clock

  • Take on an empty stomach, 1 hour before or 2 hours after meals.  Food inhibits absorption

  • Parenteral dosage form should not be run in same IV line as other medications

  • Inject intravenous injection slowly over a period of 10 minutes

Adverse Reactions (Side Effects):

  • Hypersensitivity

  • Gastrointestinal: nausea, vomiting, diarrhea

  • Vaginitis  

Dosage:

Administered orally (capsules and oral suspension) and injectable

  • Oral

    • Adult and children (>40kg):

      • 500mg q4-6h (may increase to 1 gram q4-6h for severe infections)

    • Infants and children (<40kg):

      • 50mg/kg/day in divided doses every 6 hours

    • Neonates (>2kg) (age < 7 days):

      • 75mg/kg/day divided every 8 hours

    • Neonates (>2kg) (age > 7 days):

      • 150mg/kg/day every 6 hours

    • Neonates (<2kg):

      • 50mg/kg/day divided every 12 hours

  • Injectable

    • Adult and children (>40kg):

      • 250-500mg IM or IV q4-6h (up to 1 gram q-46h for severe infections)

    • Infants and children (<40kg):

      • 50mg/kg/day IM or IV in equally divided doses every 6 hours

      • severe infections: 100mg/kg/day IM or IV in equally divided doses every 4-6 hours

    • Premature/Neonates:

      • 25mg/kg/day IM or IV in divided doses

 

Approved for public release; Distribution is unlimited.

The listing of any non-Federal product in this CD is not an endorsement of the product itself, but simply an acknowledgement of the source. 

Operational Medicine 2001

Health Care in Military Settings

Bureau of Medicine and Surgery
Department of the Navy
2300 E Street NW
Washington, D.C
20372-5300

Operational Medicine
 Health Care in Military Settings
CAPT Michael John Hughey, MC, USNR
NAVMED P-5139
  January 1, 2001

 United States Special Operations Command
7701 Tampa Point Blvd.
MacDill AFB, Florida
33621-5323

*This web version is provided by The Brookside Associates Medical Education Division.  It contains original contents from the official US Navy NAVMED P-5139, but has been reformatted for web access and includes advertising and links that were not present in the original version. This web version has not been approved by the Department of the Navy or the Department of Defense. The presence of any advertising on these pages does not constitute an endorsement of that product or service by either the US Department of Defense or the Brookside Associates. The Brookside Associates is a private organization, not affiliated with the United States Department of Defense.

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