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Operational Medicine 2001
Vitamin C (Ascorbic Acid)

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Category:

  • Vitamin

Description:

  • Dietary supplement; water-soluble vitamin

Indications:

  • Vitamin C deficiency

  • necessary for collagen and dentin formation and tissue repair

  • Scurvy treatment and prophylaxis

  • Antioxidant

  • Urine acidifier (at high doses >2 grams per day)

  • Idiopathic methemoglobinemia (150mg per day)

Contraindications:

  • No significant contraindications.

Precautions:

  • Pregnancy category C

  • Excessive vitamin C doses may should not be adminstered to patients with diabetes, prone to renal calculi, undergoing stool occult blood tests, sodium restrictive diets or on anticoagulants.

  • High dose administration to pregnant women may cause the fetus to become “sensitized” to the levels and may experience “withdrawa” after delivery.

  • Some products contain tartrazine and/or sulfite, use in caution in patients who are sensitive to these agents.

  • Ascorbic acid increases serum levels of estrogens, use caution in patients receiving estrogen replacement therapy or oral contraceptives.

  • Ascorbic acid may reduce the anticoagulant effect of warfarin.

  • Large dose of vitamin C (>500mg) may cause false-positive urine glucose determinations.

  • Do not administer vitamin C within 48-72 hours of an stool occult blood test due to false negatives.

Adverse Reactions (Side Effects):

  • Relatively non-toxic in therapeutic doses

  • Large dose may cause diarrhea and precipitation of renal stones.

  • Transient mild soreness may occur at IM or SQ injection site.

  • Too rapid of IV administration may cause temporary faintness or dizziness.

Dosage:

  • Dietary sources: citric juices, fresh vegetables and fruit, potatoes

  • Administered orally or IV

  • Dietary supplementation (RDA: recommended daily allowance):

    • Adults: 60mg per day

  • Scurvy: 100-300mg per day over several days will reverse scurvy effects

  • Infants:

    • preventive: 30mg per day

    • treatment: 100-300mg per day

    • Premature infants: 75-100mg per day

  • Enhanced wound healing: 300-500mg per day for 7-10 days pre- and post-operatively

  • Burn patients: 1-2 grams per day

 

Approved for public release; Distribution is unlimited.

The listing of any non-Federal product in this CD is not an endorsement of the product itself, but simply an acknowledgement of the source. 

Operational Medicine 2001

Health Care in Military Settings

Bureau of Medicine and Surgery
Department of the Navy
2300 E Street NW
Washington, D.C
20372-5300

Operational Medicine
 Health Care in Military Settings
CAPT Michael John Hughey, MC, USNR
NAVMED P-5139
  January 1, 2001

 United States Special Operations Command
7701 Tampa Point Blvd.
MacDill AFB, Florida
33621-5323

*This web version is provided by The Brookside Associates Medical Education Division.  It contains original contents from the official US Navy NAVMED P-5139, but has been reformatted for web access and includes advertising and links that were not present in the original version. This web version has not been approved by the Department of the Navy or the Department of Defense. The presence of any advertising on these pages does not constitute an endorsement of that product or service by either the US Department of Defense or the Brookside Associates. The Brookside Associates is a private organization, not affiliated with the United States Department of Defense.

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