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Operational Medicine 2001
Vitamin B6 (Pyridoxine)

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Category:

  • Vitamin

Description:

  • Dietary supplement; water-soluble vitamin

Indications:

  • Vitamin B6 deficiency

    • seen in some breast-fed infants, elderly, oral contraceptive users, alcoholics

  • necessary for proper red blood cell production

  • Adjunct to Isoniazid (INH) therapy

  • Unlabed uses:

    • hydrazine poisoing

    • premenstrual syndrome

    • hyperoxaluria type I

    • nausea and vomiting in pregnancy

Contraindications:

Precautions:

  • Pregnancy category A

  • Patients may develop hypervitaminosis B6 with excessive dosages.  Symtoms of hypervitaminosis B6 are ataxia and severe sensory neuropathy.  This takes up to six months to normalize once discontinued.

Adverse Reactions (Side Effects):

  • Relatively non-toxic in therapeutic doses

  • Sensory neuropathic syndrome (unstable gait, numb feet, awkward hands, perioral numbness, decreased touch sensations, paresthesia)

  • Low serum folic acid levels  

Dosage:

  • Dietary sources: meats, cereals, lentils, nuts, bananas, avocados, potatoes

  • Administered in oral soft gelatin capsules or injection

  • Dietary supplementation (RDA: recommended daily allowance):

    • Adult males: 2m per day

    • Adults females: 1.6m per day

  • Dietary deficiency: 10-20mg per day for 3 weeks

  • Vitamin B6 dependency syndrome: 600mg per day initially, then 30mg per day for life

  • Isoniazid deficiency: 50-200mg per day

  • Isoniazid poisoning: 4 grams IV initial, followed by 1 gram IM every 30 minutes

 


Approved for public release; Distribution is unlimited.

The listing of any non-Federal product in this CD is not an endorsement of the product itself, but simply an acknowledgement of the source. 

Operational Medicine 2001

Health Care in Military Settings

Bureau of Medicine and Surgery
Department of the Navy
2300 E Street NW
Washington, D.C
20372-5300

Operational Medicine
 Health Care in Military Settings
CAPT Michael John Hughey, MC, USNR
NAVMED P-5139
  January 1, 2001

United States Special Operations Command
7701 Tampa Point Blvd.
MacDill AFB, Florida
33621-5323

*This web version is provided by The Brookside Associates Medical Education Division.  It contains original contents from the official US Navy NAVMED P-5139, but has been reformatted for web access and includes advertising and links that were not present in the original version. This web version has not been approved by the Department of the Navy or the Department of Defense. The presence of any advertising on these pages does not constitute an endorsement of that product or service by either the US Department of Defense or the Brookside Associates. The Brookside Associates is a private organization, not affiliated with the United States Department of Defense.

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