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Operational Medicine 2001
Praziquantel (Biltricide)

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Category:

  • Miscellaneous

Description:

  • Anthelmintic

Indications:

  • Schistosomiasis caused by Schistosoma spp. pathogenic to humans

  • Clonorchiasis and opisthorchiasis (liver flukes)

  • Cysticercosis (non FDA approved)

  • Intestinal cestode (tapeworm) infections (non FDA approved)

Contraindications:

  • Ocular cysticercosis

Precautions:

  • Pregnancy category B; do not nurse on day of treatment and during the subsequent 72 hours

  • Children <4 years

  • Cerebral cysticercosis (hospitalize patient for duration of therapy)

Adverse Reactions (Side Effects):

  • CNS: dizziness, drowsiness, fever, headache

  • GI: abdominal discomfort, minimal increases in liver enzymes

  • SKIN: urticaria

  • MISC: malaise

 

Dosage:

Administered orally

  • Adult and child:  

    • Schistosomiasis: PO 20 mg/kg/dose 2-3 times daily for 1 day at 4-6 hour intervals

    • Clonorchiasis and opisthorchiasis: PO 75 mg/kg/day divided every 8 hours for 1-2 days

    • Cysticercosis: PO 50 mg/kg/day divided every 8 hours for 14 days (administer steroids prior to starting praziquantel for neurocysticercosis)

    • Cestodes: PO 10-20 mg/kg as a single dose (25 mg/kg for Hymenolepsis nana)

Special considerations:

  • Swallow tablets unchewed with some liquid during meals

  • May cause drowsiness

  • Use caution driving or performing tasks requiring mental alertness

Approved for public release; Distribution is unlimited.

The listing of any non-Federal product in this CD is not an endorsement of the product itself, but simply an acknowledgement of the source. 

Operational Medicine 2001

Health Care in Military Settings

Bureau of Medicine and Surgery
Department of the Navy
2300 E Street NW
Washington, D.C
20372-5300

Operational Medicine
 Health Care in Military Settings
CAPT Michael John Hughey, MC, USNR
NAVMED P-5139
  January 1, 2001

 United States Special Operations Command
7701 Tampa Point Blvd.
MacDill AFB, Florida
33621-5323

*This web version is provided by The Brookside Associates Medical Education Division.  It contains original contents from the official US Navy NAVMED P-5139, but has been reformatted for web access and includes advertising and links that were not present in the original version. This web version has not been approved by the Department of the Navy or the Department of Defense. The presence of any advertising on these pages does not constitute an endorsement of that product or service by either the US Department of Defense or the Brookside Associates. The Brookside Associates is a private organization, not affiliated with the United States Department of Defense.

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