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Operational Medicine 2001
Penicillin G Procaine (Wycillin)

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Category:

  • Antibiotic

Description:

  • Penicillin, Natural

Indications:

Contraindications:

  • Never use IV

Precautions:

  • Pregnancy category B

  • Use with caution in patients with penicillin or cephalosporin allergy (5-10% chance of cross-reactivity)

  • Deep intramuscular injection only into the upper, outer quadrant of the buttocks

Adverse Reactions (Side Effects):

  • Hypersensitivity

  • Gastrointestinal: nausea, vomiting, diarrhea

  • Vaginitis  

Dosage:

Administered by IM injection ONLY

  • Pneumococcal infections:

    • Adult: 600,000 to 1 million units per day

    • Children (<60kg): 300,000 units per day

  • Streptococcal infections (Group A):

    • Adult: 600,000 to 1 million units per day

    • Children (<60kg): 300,000 units per day

  • Bacterial endocarditis:

    • Adult: 600,000 to 1 million units per day

  • Staphylococcal infections:

    • Adult: 600,000 to 1 million units per day

    • Children (<60kg): 300,000 units per day

  • Rat-bite fever

    • Adult: 600,000 to 1 million units per day

  • Erysipeloid endocarditis

    • Adult: 600,000 to 1 million units per day

  • Diphtheria

    • Adjunct to antitoxin: 300,000-600,000 units per day

    • Carrier state: 300,000 units per day for 10 days

  • Anthrax (cutaneous):

    • 600,000 to 1 million units per day for 10 days

  • Syphilis:

    • Primary, secondary and latent: 600,000 units per day for 8 days

    • Late (tertiary, neurosyphilis): 600,000 units per day for 10-15 days

    • Neurosyphilis: 2.4 million units per day (with probenecid 500mg orally qid) for 10-14 days

    • Congenital: 50,000 units/kg/day (one IM dose) for 10 days

  • Yaws (bejel and pinta): 

    • treat same as syphilis in corresponding stage of disease

  • Gonorrheal infections:

    • 4.8 million units divided into at least two doses at one visit with 1 gram of probenecid between doses

  • Vincent’s gingivitis and pharyngitis:

    • 600,000 to 1 million units per day

 

Approved for public release; Distribution is unlimited.

The listing of any non-Federal product in this CD is not an endorsement of the product itself, but simply an acknowledgement of the source. 

Operational Medicine 2001

Health Care in Military Settings

Bureau of Medicine and Surgery
Department of the Navy
2300 E Street NW
Washington, D.C
20372-5300

Operational Medicine
 Health Care in Military Settings
CAPT Michael John Hughey, MC, USNR
NAVMED P-5139
  January 1, 2001

 United States Special Operations Command
7701 Tampa Point Blvd.
MacDill AFB, Florida
33621-5323

*This web version is provided by The Brookside Associates Medical Education Division.  It contains original contents from the official US Navy NAVMED P-5139, but has been reformatted for web access and includes advertising and links that were not present in the original version. This web version has not been approved by the Department of the Navy or the Department of Defense. The presence of any advertising on these pages does not constitute an endorsement of that product or service by either the US Department of Defense or the Brookside Associates. The Brookside Associates is a private organization, not affiliated with the United States Department of Defense.

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