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Operational Medicine 2001
Alendronate (Fosamax)

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Category:

  • Miscellaneous

Description:

  • Bone resorption inhibitor, antiosteoporotic

Indications:

  • Treatment and prophylaxis of osteoporosis in postmenopausal women

  • Paget’s disease of the bone

Contraindications:

  • Hypocalcemia, esophageal abnormalities, delayed esophageal emptying

  • Patient unable to stand or sit upright for at least 30 minutes after administration

Precautions:

  • Pregnancy category C

  • CrCl < 35 ml/min

  • Uncorrected mineral deficiencies (i.e. calcium, vitamin D)

Adverse Reactions (Side Effects):

  • CNS: headache

  • GI: abdominal distention, abdominal pain, acid regurgitation, dysphagia, esophageal ulcer, flatulence, gastritis

  • METAB: hypocalcemia, hypophosphatemia

  • MS: musculoskeletal pain

  • SKIN: erythema, rash

  • MISC: drug fever

Dosage:

Administered orally (tablet)

Adult:

  • Osteoporosis (prophylaxis): 

    • PO 5mg daily

  • Osteoporosis (treatment): 

    • PO 10mg daily

  • Paget’s disease: PO 40mg daily for 6 months

Note: 

  • Patients should take medication upon rising in the morning, with a full glass of water on an empty stomach

  • Remain upright for at least 30 minutes.  

  • Do not eat for at least 30-60 minutes after the dose.

 

 

Approved for public release; Distribution is unlimited.

The listing of any non-Federal product in this CD is not an endorsement of the product itself, but simply an acknowledgement of the source. 

Operational Medicine 2001

Health Care in Military Settings

Bureau of Medicine and Surgery
Department of the Navy
2300 E Street NW
Washington, D.C
20372-5300

Operational Medicine
 Health Care in Military Settings
CAPT Michael John Hughey, MC, USNR
NAVMED P-5139
  January 1, 2001

 United States Special Operations Command
7701 Tampa Point Blvd.
MacDill AFB, Florida
33621-5323

*This web version is provided by The Brookside Associates Medical Education Division.  It contains original contents from the official US Navy NAVMED P-5139, but has been reformatted for web access and includes advertising and links that were not present in the original version. This web version has not been approved by the Department of the Navy or the Department of Defense. The presence of any advertising on these pages does not constitute an endorsement of that product or service by either the US Department of Defense or the Brookside Associates. The Brookside Associates is a private organization, not affiliated with the United States Department of Defense.

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