Appendix C: Comparative Lethality of Selected Toxins
And Chemical Agents in Laboratory Mice
|
AGENT |
LD50 |
MOLECULAR WEIGHT |
SOURCE |
|
Botulinum toxin |
0.001 |
150,000 |
Bacterium |
|
Shiga toxin |
0.002 |
55,000 |
Bacterium |
|
Tetanus toxin |
0.002 |
150,000 |
Bacterium |
|
Abrin |
0.04 |
65,000 |
Plant (Rosary Pea) |
|
Diphtheria toxin |
0.10 |
62,000 |
Bacterium |
|
Maitotoxin |
0.10 |
3,400 |
Marine Dinoflagellate |
|
Palytoxin |
0.15 |
2,700 |
Marine Soft Coral |
|
Ciguatoxin |
0.40 |
1,000 |
Marine Dinoflagellate |
|
Textilotoxin |
0.60 |
80,000 |
Elapid Snake |
|
C. perfringens toxins |
0.1 - 5.0 |
35-40,000 |
Bacterium |
|
Batrachotoxin |
2.0 |
539 |
Arrow-Poison Frog |
|
Ricin |
3.0 |
64,000 |
Plant (Castor Bean) |
|
alpha-Conotoxin |
5.0 |
1,500 |
Cone Snail |
|
Taipoxin |
5.0 |
46,000 |
Elapid Snake |
|
Tetrodotoxin |
8.0 |
319 |
Puffer Fish |
|
alpha-Tityustoxin |
9.0 |
8,000 |
Scorpion |
|
Saxitoxin |
10.0 (Inhal 2.0) |
299 |
Marine Dinoflagellate |
|
VX |
15.0 |
267 |
Chemical Agent |
|
SEB (Rhesus/Aerosol) |
27.0 (ED50~pg) |
28,494 |
Bacterium |
|
Anatoxin-A(s) |
50.0 |
500 |
Blue-Green Algae |
|
Microcystin |
50.0 |
994 |
Blue-Green Algae |
|
Soman (GD) |
64.0 |
182 |
Chemical Agent |
|
Sarin (GB) |
100.0 |
140 |
Chemical Agent |
|
Aconitine |
100.0 |
647 |
Plant (Monkshood) |
|
T-2 Toxin |
1,210.0 |
466 |
Fungal Mycotoxin |