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Military Obstetrics & Gynecology
Laboratory

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Prolactin

Prolactin is a hormone, released from the pituitary gland, that stimulates milk production.

Mild elevations of prolactin can follow a breast exam, because breast stimulation provokes increased release of prolactin.

High levels of prolactin are frequently due to a pituitary tumor (microadenoma or macroadenoma) and are often associated with amenorrhea and glactorrhea.

Elevations of Prolactin may be seen in:

  • Galactorrhea
  • Amenorrhea
  • Pituitary malfunction
  • Hypothyroidism
  • Renal failure
  • Pregnancy
  • Breast-feeding
  • Stress
  • Exercise
  • Nipple stimulation
  • Drugs (estrogen, tricyclic antidepressents, antihypertensives, etc.)

Normal Values*

Men <20 ng/ml
Women 2-15 ng/ml
Pregnancy 50-400 ng/ml

*These are general values taken from a variety of sources. The actual normal values may vary from lab to lab and from one type of testing protocol to another.

Source: Operational Medicine 2001,  Health Care in Military Settings, NAVMED P-5139, May 1, 2001, Bureau of Medicine and Surgery, Department of the Navy, 2300 E Street NW, Washington, D.C., 20372-5300

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