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Military Obstetrics & Gynecology
Laboratory

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Cryoglobulin

Cryoglobins are unusual proteins that precipitate out of solution at low temperatures and reversibly re-dissolve on warming. Their presence is associated with:
  • Auto-immune diseases, including:
    • Poststreptococcal glomerulonephritis
    • Rheumatoid arthritis
    • Lupus
    • Sjoegren's syndrome
    • Polyarteritis nodosum
  • Infectious illnesses, including:
    • Mononucleosis
    • Syphilis
    • Cytomegalovirus
    • Leprosy
    • Sarcoidosis
  • Malignancies, specifically:
    • Multiple myeloma
    • Chronic lymphocytic leukemia
    • Lymphosarcoma
  • Liver disease, hemolytic disease, and ulcerative colitis

Normal Values*

Men-Women Negative

*These are general values taken from a variety of sources. The actual normal values may vary from lab to lab and from one type of testing protocol to another.

The information contained here is an abbreviated summary. For more detailed and complete information, consult the manufacturer's product information sheets or standard textbooks

Source: Operational Medicine 2001,  Health Care in Military Settings, NAVMED P-5139, May 1, 2001, Bureau of Medicine and Surgery, Department of the Navy, 2300 E Street NW, Washington, D.C., 20372-5300

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